| Huang Y, Yu SH, Zhen WX, et al. Tanshinone I, a new EZH2 inhibitor restricts normal and malignant hematopoiesis through upregulation of MMP9 and ABCG2[J]. Theranostics, 2021; 11(14):6891-6904. | |||
| Journal | Theranostics | IF(2021) | 11.556 |
| doi | 10.7150/thno.53170 | Product | EZH2&SUZ12 |
| Services | Recombinant Protein Production | ||
| Zebrafish EZH2(Detai Bio) / SUZ12(Detai Bio) | |||
| Xu WF, Che Y, Zhang Q, et al. Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition[J]. Cell metabolism. 2021, 33(2):424-436. | |||
| Journal | Cell metabolism | IF(2021) | 27.287 |
| doi | 10.1016/j.cmet.2020.11.018 | Product | CASPASE-4 |
| Services | Recombinant Protein Production | System | Mammalian Expression |
| Human CASPASE-4-pcDNA3.1(-)-AMP-His(Detai Bio) Human CASPASE-4-pcDNA3.1(-)-AMP-HA(Detai Bio) Human CASPASE-4(1-90AA)-pcDNA3.1(-)-AMP-His(Detai Bio) Recombinant pro-caspase-4-eGFP-His(Detai Bio) Recombinant pro-caspase-11-eGFP-His(Detai Bio) Recombinant caspase-4 (CARD)-Fc-HA(Detai Bio) |
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| Xu WF, Zhang Q, Ding CJ, et al. Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure[J]. Acta Pharmacologica Sinica. 2021(42), 68-76. | |||
| Journal | Acta Pharmacologica Sinica | IF(2021) | 6.15 |
| doi | 10.1038/s41401-020-0434-2 | Product | caspase 4 |
| Services | Recombinant Protein Production | System | Mammalian Expression |
| active caspase-4-GFP was ordered from DeTai Bio | |||
| Xia AH, Li X, Quan JJ, et al. Mycobacterium tuberculosis Rv0927c Inhibits NF-κB Pathway by Downregulating the Phosphorylation Level of IκBα and Enhances Mycobacterial Survival[J]. Frontiers in immunology, 2021(12):721370. | |||
| Journal | Frontiers in immunology | IF(2021) | 7.561 |
| doi | 10.3389/fimmu.2021.721370 | Product | Rv0927c |
| Services | Recombinant Protein Production | System | Bacterial Expression |
| Rv0927c gene was synthesized and ligated into pET30a(+) expression vector (DetaiBio, Nanjing, China). | |||
| Xu S, Jing M, Kong DM, et al. Chitin binding protein from the kuruma shrimp Marsupenaeus japonicus facilitates the clearance of Vibrio anguillarum[J]. Developmental & Comparative Immunology, 2021(117), 103981. | |||
| Journal | Developmental & Comparative Immunology | IF(2021) | 3.636 |
| doi | 10.1016/j.dci.2020.103981 | ||
| Services | Peptide Synthesis | ||
| A peptide synthesis service was offered by biology company DETAIBIO (Nanjing China), | |||
| Sun BQ, Xue YF., Du XL, et al. Identification of genetic determinants of hemolytic activity of Riemerella anatipestifer using random transposon mutagenesis[J]. Veterinary research, 2021(52), 19. | |||
| Journal | Veterinary research | IF(2021) | 3.699 |
| doi | 10.1186/s13567-021-00900-6 | ||
| Services | Protein purification | ||
| The soluble recombinant proteins rRiean_0317, rRiean_0653, and rRiean_1143 were purified by Ni-iminodiacetic acid affinity chromatography (Detai Bio-Tech (Nanjing) Co., Ltd., Nanjing, China) | |||
| Li X, Bai LJ, Zhang YH, et al. Novel GLP-1/anti-apolipoprotein B bifunctional fusion protein alleviates diabetes and diabetic complications in combination with low-intensity ultrasound[J]. Life Sciences, 2021(278):119549. | |||
| Journal | Life Sciences | IF(2021) | 5.037 |
| doi | 10.1016/j.lfs.2021.119549 | ||
| Services | Recombinant Protein Production | System | Mammalian Expression |
| All bifunctional fusion proteins were entrusted to Nanjing Detai Bio Co., Ltd. for gene synthesis and recombinant protein expression with purity higher than 98%. | |||
| Shao W, Hao ZY, Chen YF, et al. OIP5-AS1 specifies p53-driven POX transcription regulated by TRPC6 in glioma[J]. Journal of molecular cell biology, 2021, 13(6):409-421. | |||
| Journal | Journal of molecular cell biology | IF(2021) | 6.216 |
| doi | 10.1093/jmcb/mjab001 | ||
| Services | Protein purification | ||
| Human p53 protein was purified (Detai Bio) | |||
| Huang FY, Sun LY, Zhao C, et al. Protein microcapsules integrated hierarchical scaffolds for local treatment of acute myocardial infarction model[J]. Applied Materials Today, 2021(22), 100901 | |||
| Journal | Applied Materials Today | IF(2021) | 10.041 |
| doi | 10.1016/j.apmt.2020.100901 | Product | Recombinant ACE2 |
| Services | Recombinant Protein Production | System | Bacterial Expression |
| Recombinant ACE2 (AA18-740) protein synthetized from E. coli expression system was provided by Nanjing Detai Bio-technology Co, Ltd | |||
| Gao DD, Jin N, Fu YX, et al. Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors[J]. European Journal of Medicinal Chemistry, 2021(216):113333. | |||
| Journal | European Journal Of Medicinal Chemistry | IF(2021) | 6.514 |
| doi | 10.1016/j.ejmech.2021.113333 | Product | STAT3 |
| Services | Recombinant Protein Production | System | Bacterial Expression |
| Purified STAT3 protein (His-tag 127-722 amino acid, DetaiBio, China) | |||
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