| 名称 | Human BCMA Protein |
| 宿主细胞 | HEK293 |
| 纯化方法 | The soluble target protein Human-BCMA was derived from secreted expression and was purified by affinity chromatography. |
| 纯度 | >95% by SDS-PAGE & HPLC |
| 基因名 | BCMA |
| 物种 | Human |
| 标签 | His |
| 缓冲液 | 1×PBS,pH7.4 |
| 储存方式 | For long term use, aliquot and store at -80°C (avoiding multiple freeze-thaws). |
| SDS-PAGE |
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| HPLC |
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| ELISA |
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The protein is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
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