Human PD-L1 Protein

产品名称	Human PD-L1 Protein
产品货号	DTD0640
产品规格
价格

产品详情

名称	Human PD-L1 Protein
宿主细胞	HEK293
纯度	>95% by SDS-PAGE & HPLC
基因名	CD274
物种	Human
标签	His
缓冲液	1×PBS，pH7.4
储存方式	For long term use, aliquot and store at -80°C (avoiding multiple freeze-thaws).
SDS-PAGE
HPLC
ELISA

产品说明书
产品说明书

Programmed death-ligand 1 (PD-L1, also known as CD274 or B7-H1) is a type I transmembrane protein and a key immune checkpoint molecule. It is widely expressed in various cell types, including tumor cells, antigen-presenting cells, and other immune-related tissues. PD-L1 interacts with its receptor PD-1 on T cells to inhibit T cell activation and proliferation, thereby promoting immune tolerance and preventing autoimmune responses. However, many tumors exploit this pathway to evade immune surveillance by upregulating PD-L1 expression. The PD-1/PD-L1 axis has become a central target in cancer immunotherapy, with multiple FDA-approved therapeutic antibodies blocking this interaction to restore anti-tumor immunity.

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发货时间：确认订单并完成付款后1~2个工作日内安排发货。
发货方式：冰袋或干冰。