| 名称 | B-cell differentiation antigen CD72 Protein |
| 纯度 | >50% |
| 宿主细胞 | HEK293 |
| 序列 | MADAITYADLRFVKVPLKNSASNHLGQDCEAYEDGELTYENVQVSPVPGGPPGLASPALADKAGVGSEQPTATWSSVNSSALRQIPRCPTVCLQYFLLGLLVSCLMLGVAVICLGVRYLQVSRQFQEGTRIWEATNSSLQQQLREKISQLGQKEVELQKARKELISSQDTLQEKQRTHEDAEQQLQACQAERAKTKENLKTEEERRRDLDQRLTSTRETLRRFFSDSSDTCCPCGWIPYQERCFYISHTLGSLEESQKYCTSLSSKLAAFDEPSKYYYEVSLPSGLEELLDRSKSYWIQMSKKWRQDSDSQSRHCVRIKTYYQKWERTISKCAELHPCICESEAFRFPDGINLN |
| 基因名 | CD72 |
| Uniprot ID | P21855 |
| 物种 | Mus musculus(Mouse) |
| 产品性状 | Liquid |
| 缓冲液 | 1×PBS,5% Glycerol,pH7.4 |
| 储存方式 | -80 ℃ packaging and storage to avoid repeated freezing and thawing. |
| SDS-PAGE &WB |
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Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions (PubMed:10549631). Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling (PubMed:27810925). Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling (PubMed:9590210). Acts also as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis (PubMed:9723705, PubMed:24950378).
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