B-cell differentiation antigen CD72 Protein

产品名称	B-cell differentiation antigen CD72 Protein
产品货号	DTD0108
产品规格
价格

产品详情

名称	B-cell differentiation antigen CD72 Protein
纯度	>85%
宿主细胞	HEK293
序列	MADAITYADLRFVKVPLKNSASNHLGQDCEAYEDGELTYENVQVSPVPGGPPGLASPALADKAGVGSEQPTATWSSVNSSALRQIPRCPTVCLQYFLLGLLVSCLMLGVAVICLGVRYLQVSRQFQEGTRIWEATNSSLQQQLREKISQLGQKEVELQKARKELISSQDTLQEKQRTHEDAEQQLQACQAERAKTKENLKTEEERRRDLDQRLTSTRETLRRFFSDSSDTCCPCGWIPYQERCFYISHTLGSLEESQKYCTSLSSKLAAFDEPSKYYYEVSLPSGLEELLDRSKSYWIQMSKKWRQDSDSQSRHCVRIKTYYQKWERTISKCAELHPCICESEAFRFPDGINLN
基因名	CD72
Uniprot ID	P21855
物种	Mus musculus(Mouse)
产品性状	Liquid
缓冲液	1×PBS，5% Glycerol，pH7.4
储存方式	-80 ℃ packaging and storage to avoid repeated freezing and thawing.
SDS-PAGE &WB

产品说明书产品说明书

Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions (PubMed:10549631). Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling (PubMed:27810925). Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling (PubMed:9590210). Acts also as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis (PubMed:9723705, PubMed:24950378).

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发货方式：冰袋或干冰。