重组人lgG4 FC蛋白

产品名称	Human IgG4 CH23 Protein
产品货号	DTP0163
产品规格
价格

产品详情

名称	Human IgG4 CH23 Protein
纯度	＞90% as determined by SDS-PAGE&HPLC
表达宿主	293 Cells
标签	His
种属	Human
分子量	32 kDa
缓冲液	50mM Tris, 300mM NaCl, 5%Sucrose, PH:8.5
稳定性 & 储存条件	-80 ℃ packaging and storage to avoid repeated freezing and thawing.
SDS-PAGE
HPLC

产品说明书产品说明书

Immunoglobulin G4 (IgG4) is a member of immunoglobulin G produced and secreted by many effective B cells. After gastric protease cleavage, IgG is divided into two F (ab) fragments, each with an antigen binding site and a highly conserved Fc fragment. The Fc segment has highly conserved N-glycosylation sites. The Fc region of the Igγ-4 chain contains two constant regions (CH2, CH3) of the IgG4 H chain. The characteristic of IgG4 is its ability to form semi antibody molecules through a process called Fab arm exchange, which can lead to the production of bispecific antibodies. Compared with other IgG, this subclass has less inflammation and plays an important role in immune tolerance and regulation. It is used for research and therapeutic applications, particularly for developing antibodies for autoimmune diseases and cancer treatment.

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发货方式：冰袋或干冰。