Anti-CD43 Antibody, mAb

产品名称	Anti-CD43 Antibody, mAb
产品货号	DTA0651
产品规格
价格

产品详情

类型	Monoclonal
特异性	This antibody recognizes CD43 molecules.
Clone号	DF-T1
免疫宿主	Mouse
亚型	IgG
纯化方法	Purified by Protein A
验证应用平台	Flow Cyt / IHC
状态	Liquid
缓冲液	PBS，pH7.4
储存方式	Shipped in ice bag. The antibody can be stored for 1-2 weeks at 2 -8°C. For long term storage, store it at -20°C. Avoid repeated freezing and thawing cycles.

产品说明书产品说明书

CD43 is a heavily sialylated transmembrane glycoprotein that plays a role in T-cell activation and immune regulation. Structurally, it consists of a mucin-like extracellular domain rich in serine and threonine residues, which supports extensive O-glycosylation and contains a potential N-glycosylation site; a transmembrane region; and a cytoplasmic tail harboring putative phosphorylation sites involved in signal transduction.

CD43 is expressed on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and certain B-cell subsets. It modulates cell adhesion, migration, and antigen-specific activation of T cells. Upon immune stimulation, CD43 can undergo ectodomain shedding—proteolytic cleavage that releases its soluble extracellular fragment into the microenvironment, a process thought to regulate leukocyte function and inflammatory responses.

While its precise signaling mechanisms remain under investigation, CD43 is recognized as an important immunoregulatory molecule with implications in autoimmunity, infection, and cancer biology. Its expression pattern and post-translational modifications make it a subject of continued interest in both basic immunology and translational research.

物流平台：默认为京东物流。若有其他需求，请联系对接销售。
发货时间：确认订单并完成付款后1~2个工作日内安排发货。
发货方式：冰袋或干冰。