Anti-CD45 Antibody, mAb

产品名称	Anti-CD45 Antibody, mAb
产品货号	DTA0652
产品规格
价格

产品详情

类型	Monoclonal
特异性	This antibody recognizes CD45 molecules.
Clone号	2D1
免疫宿主	Mouse
亚型	IgG
纯化方法	Purified by Protein A
验证应用平台	Flow Cyt / IHC
状态	Liquid
缓冲液	PBS，pH7.4
储存方式	Shipped in ice bag. The antibody can be stored for 1-2 weeks at 2 -8°C. For long term storage, store it at -20°C. Avoid repeated freezing and thawing cycles.

产品说明书产品说明书

CD45, also known as Leukocyte Common Antigen (LCA), is a transmembrane glycoprotein universally expressed on the surface of all nucleated hematopoietic cells. It functions as a key regulator of immune cell signaling through its intracellular protein tyrosine phosphatase (PTPase) activity, which modulates the activation of Src-family kinases such as Lck and Fyn in T and B lymphocytes. Structurally, CD45 consists of a heavily glycosylated extracellular domain, a single-pass transmembrane region, and a cytoplasmic tail containing two PTPase domains. Alternative splicing of exons encoding its extracellular region generates multiple isoforms, including CD45RA, CD45RB, CD45RC, and CD45RO, which are differentially expressed during leukocyte development and activation. For example, CD45RA marks naïve T cells, while CD45RO is associated with activated and memory T cells. Due to its pan-leukocyte expression and isoform-specific patterns, CD45 serves as an essential marker for immunophenotyping in research, diagnostics, and flow cytometry, and plays a critical role in both adaptive and innate immune responses.

物流平台：默认为京东物流。若有其他需求，请联系对接销售。
发货时间：确认订单并完成付款后1~2个工作日内安排发货。
发货方式：冰袋或干冰。