Anti-IL-12 Antibody, mAb

产品名称	Anti-IL-12 Antibody, mAb
产品货号	DTA0674
产品规格
价格

产品详情

类型	Monoclonal
特异性	This antibody recognizes IL-12 molecules.
配对抗体	DTA0673
免疫宿主	Mouse
亚型	IgG1
纯化方法	Purified by Protein A
验证应用平台	ELISA
状态	Liquid
缓冲液	PBS，pH7.4
储存方式	Shipped in ice bag. The antibody can be stored for 1-2 weeks at 2 -8°C. For long term storage, store it at -20°C. Avoid repeated freezing and thawing cycles.

产品说明书产品说明书

IL-12 (Interleukin-12) is a heterodimeric cytokine composed of two subunits, p35 (IL-12α) and p40 (IL-12β), primarily produced by antigen-presenting cells such as dendritic cells, macrophages, and B cells. It serves as a critical bridge between innate and adaptive immunity by promoting the differentiation of naïve T cells into T helper 1 (Th1) cells, enhancing interferon-gamma (IFN-γ) production, and boosting the cytotoxic activity of natural killer (NK) and CD8^⁺ T cells.

Due to its potent role in driving cellular immune responses, IL-12 has been extensively studied in the context of infectious diseases, cancer immunotherapy, and vaccine development. It enhances antitumor immunity by stimulating IFN-γ-dependent pathways and improving antigen presentation. Clinically, recombinant IL-12 has been explored as an immunotherapeutic agent, though its systemic use is limited by toxicity. Current strategies focus on localized delivery or IL-12-based gene therapies to harness its immune-stimulating potential while minimizing adverse effects. Dysregulation of IL-12 is also implicated in autoimmune and inflammatory disorders, highlighting its dual role in immune activation and pathology.

物流平台：默认为京东物流。若有其他需求，请联系对接销售。
发货时间：确认订单并完成付款后1~2个工作日内安排发货。
发货方式：冰袋或干冰。