| 类型 | Monoclonal |
| 特异性 | This antibody recognizes IL-6 molecules. |
| 免疫宿主 | Rat |
| 亚型 | IgG2a |
| 纯化方法 | Purified by Protein A |
| 验证应用平台 | ELISA |
| 状态 | Liquid |
| 缓冲液 | PBS,pH7.4 |
| 储存方式 | Shipped in ice bag. The antibody can be stored for 1-2 weeks at 2 -8°C. For long term storage, store it at -20°C. Avoid repeated freezing and thawing cycles. |
IL-6 (Interleukin-6) is a key pleiotropic cytokine that regulates immune responses, inflammation, hematopoiesis, and the acute-phase reaction. It is produced by various cells upon infection or injury, promoting B- and T-cell activation, Th17 differentiation, and hepatic synthesis of acute-phase proteins like CRP. As an early and sensitive biomarker of infection, IL-6 levels rise rapidly but lack specificity, as elevations also occur in autoimmune diseases, cancer, and chronic inflammation. Dysregulated IL-6 signaling is implicated in conditions such as rheumatoid arthritis, cytokine storm, and multiple myeloma, making it a major therapeutic target. Antibodies against IL-6 or its receptor are clinically used to modulate excessive immune activation.
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